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For those who do not achieve glycemic targets with lifestyle therapy, metformin, and SGLT2i, or who cannot tolerate these agents, whether due to adverse events or because other restrictions apply, other medications are recommended

Symptoms, examination, medication history, eye care, and imaging may also be necessary

Many women with PCOS also have a hard time using insulin, which is a hormone that helps control blood sugar levels

GLP-1 receptor agonists have demonstrated the ability to stimulate calcitonin secretion in animal studies, raising theoretical concerns about MTC growth or recurrence

Its FDA-approved indication is the reduction of excess abdominal fat in adults with HIV-associated lipodystrophy

Orskov C, Poulsen SS, Mller M, Holst JJ