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Both also experienced weight loss, making it difficult to determine whether the improvement was due to the medication itself or weight reduction

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Moreover, these peptides are expensive to produce and induce nausea and other gastrointestinal problems that reduce patient compliance (Pearson et al., 2019)

In such cases, exploring a tirzepatide alternative or reviewing alternatives to tirzepatide that pair more comfortably with berberine may be worth considering

Evidence indicates that this dual therapy can effectively reduce albuminuria as a crucial surrogate marker for kidney damage, more so than monotherapy