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10.1007/s00253-021-11622-2 112 DobbsS

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The functional annotations for CCL11 were obtained from the UCSC Genome Browser 23

By activating GIP receptors, tirzepatide enhances insulin secretion and may improve insulin sensitivity, while GLP-1 receptor activation stimulates glucose-dependent insulin release, suppresses inappropriate glucagon secretion, slows gastric emptying, and reduces appetite through central nervous system pathways

Zinman reports he has served on the scientific advisory boards of and received honoraria or consultant fees from AstraZeneca, Boehringer Ingelheim, Eli Lilly, Janssen, Merck, Novo Nordisk and Sanofi

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