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This understanding has led to the development of GLP-1 receptor agonists (such as semaglutide and liraglutide) and dual GIP/GLP-1 receptor agonists (such as tirzepatide) as pharmaceutical treatments

Orals may do well with preference-sensitive patients, but injectables remain the backbone unless pills hit efficacy/CV parity at better net price

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Only 13 states provided coverage as of January 2026, down from 16 states in 2025, likely reflecting the significant costs of coverage and recent state budget challenges and federal funding cuts