To date, long-term studies show sustained benefits and no significant safety concerns, although researchers continue to monitor effects on muscle mass, bone health, and mental well-being as more people use them for longer periods
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doi: 10.1016/j.pain.2007.03.012
While these symptoms typically improve over time, they can be challenging for some patients to tolerate, particularly during the initial stages of treatment
2024;143(Pt 3):113537
First of all, by the nature of drug-target MR, we have to identify genetic proxies within the specific gene regions, which means limited genetic instruments and relatively low power statistics