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In critically-ill patients, supplements improved nutritional status indicators, which have a key role in prognosis of diseases (64) and adjunctive use improved symptoms of autism spectrum disorder in children and adolescents (65)

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In previous studies that compared the differentiation capacity of chondrocytes from different passages, the results indicated that cells at early passages usually generated more cartilage matrix than those at late passages upon chondroinduction ( There are several limitations in the current study

It is worth noting that the Trovato et al 315 and Caruso et al 316 studies both employed per protocol analyses, compared with the more conventional "intent to treat" methods

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