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Concerns about obesity drugs With clinical trials showing rapid weight loss among patients who take obesity drugs, some have been left wondering if shedding pounds so fast is safe

Many studies have shown a U- or J-shaped relationship between BMI and mortality, where lower and higher BMI are associated with increased mortality risk compared to normal weight BMI levels (defined as a BMI between 18.5 to 25 kg/m)

The neuroprotective potential of this combination may prove to be its most significant long-term benefit

Increase in reactive nitrogen species production in chronic obstructive pulmonary disease airways

Real-world liraglutide cohorts report ~22% of total weight loss as lean mass, with an increase in lean-mass percentage (37)

In addition, these medications may target the appetite centers in the brain, further helping to decrease cravings and the urge to overeat