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El cido graso ahora est esterificado a CoA dentro de la matriz mitocondrial y la carnitina libre se difunde al citosol a travs de la membrana por la accin de la translocasa acetilcarninitina-carnitina

Front Immunol 13 , 908076 (2022)

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Antiviral Activity Cell Culture Antiviral Activity Nirmatrelvir exhibited antiviral activity against SARS-CoV-2 (USA-WA1/2020 isolate) infection of differentiated normal human bronchial epithelial (dNHBE) cells with EC50 and EC90 values of 62 nM (31 ng/mL) and 181 nM (90 ng/mL), respectively, after 3 days of drug exposure