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Date de mise jour : 9 juil

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Eight of the participants were between the ages of 21 and 26 years

We hypothesised that varying the timing of metformin administration before a standardised nutrient load would affect glucose-lowering, and, in this proof-of-concept study, we evaluate the effects of metformin administered by intraduodenal perfusion at different time intervals (0, 30 or 60 min) before a standardised intraduodenal glucose load on plasma glucose, GLP-1 and insulin levels in metformin-treated participants with type 2 diabetes

D., van den Berg, S

Research in Sports Medicine, 28(3), 342-355