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It's not known if they cause these tumors in humans, but people with a personal or family history of thyroid cancer are ineligible for the medications

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Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (surpass-3): A randomised, open-label, parallel-group, phase 3 trial

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D., Flak, J