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To further validate the synergistic effects of multi-strain probiotics, a randomized double-blind placebo-controlled trial involving 104 women with PCOS was conducted over six months, employing a formulation combining seven probiotic strains ( Lactobacillus acidophilus UBLA-34, Lactobacillus rhamnosus UBLR-58, etc.) with fructooligosaccharides, alongside dietary and lifestyle modifications

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Because injection bypasses the skin barrier and introduces material systemically, the safety considerations are more serious and less forgiving than for a cosmetic serum