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Yu Z, Jiang N, Su W, Zhuo Y

By tagging the substrates with ubiquitin, E3 ligases provide a platform for protein-protein interactions that can modulate the activity, localization or interaction of the target proteins, thereby triggering different biological signals to regulate a variety of cellular processes including cell cycle, cell division, stress response, DNA repair and apoptosis etc 1,2,3,4

Digestion was halted with DMEM/F12 containing 10% FBS on ice

[4] Eli Lilly

Elevated NMDA receptor levels and enhanced postsynaptic long-term potentiation induced by prenatal exposure to valproic acid