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Your body's intestinal lining undergoes cellular adaptationintestinal epithelial cells reduce their responsiveness to GLP-1 and GIP signaling at the local level, meaning the medication continues to work in your brain and pancreas for weight loss and blood sugar control while your gut side effects fade

These medications are vastly different, despite being in the same medication class, agrees Jodie Pepin, Pharm.D., clinical pharmacy program manager at Harbor Health in Round Rock, Texas

Full disclosure: Im a former employee of the American Chemical Society, which publishes Journal of Medicinal Chemistry, and a current contract writer for the societys Reactions video series.

Tasali et al

No, they are intrinsically linked

This powerful duo targets the root causes of PCOS weight challenges rather than just treating symptoms