Ignoring Hydration Many side effects improve dramatically when hydration improves
FDA-approved GLP-1 peptides such as semaglutide and tirzepatide have the strongest safety data, with GoodRx confirming these prescription-only medications are safe and effective when used as directed, a status consistent with the FDA's approval of tirzepatide for chronic weight management
They help: Regulate blood sugar levels Slow gastric emptying Reduce appetite and cravings Promote weight loss Research and Efficacy Clinical trials have shown that GLP-1 medications are highly effective in lowering HbA1c levels, with many patients achieving significant weight loss
Contact your GP immediately if you experience persistent vomiting preventing fluid intake, severe abdominal pain (especially radiating to the back), signs of dehydration, unexplained hypoglycaemia, new visual symptoms, or allergic reactions
Of those, roughly 1 in 5 had an active GLP-1 prescription
In large studies, GLP-1 therapies reduced body weight by an average of 4.57 kg, body mass index by 2.07 kg/m, and waist circumference by 4.55 cm compared with placebo