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166,167 The pathophysiology of diabetic mononeuropathy includes ischemic mechanisms, such as the occlusion of the vasa nervorum leading to nerve infarction, metabolic factors, including hyperglycemia-induced oxidative stress, and the formation of advanced glycation end products, contributing to nerve damage

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This happens when the production of free radicals exceeds the level which the bodys natural antioxidant defense mechanisms can cope with

LC has been implicated in reducing inflammatory cytokines and other biomarkers

Thus, the c-Met has become a major target for cancer therapy and its inhibition is currently being tested in the clinical trials [45]

Prelims Facts GLP-1: Glucagon-Like Peptide-1 T2DM: Type 2 Diabetes Mellitus GIP: Glucose-Dependent Insulinotropic Polypeptide HS: Hidradenitis Suppurativa PCOS: Polycystic Ovary Syndrome Telogen Effluvium: Temporary hair shedding triggered by physiological stress or rapid weight loss