Theoretically, there is a possibility of negative effects, including the development of neuropathies due to misdiagnosing cobalamin, the advancement of cancer, and improper CNS development in embryos
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Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration
But "longevity peptides" is a loose label that groups together compounds working through completely different mechanisms NAD+ metabolism, telomere biology, mitochondrial signaling, and gene expression
Among these, the class III phosphatidylinositol 3-kinase (PI3K-III) complex, comprising Vps34, Beclin-1, Vps15 and Atg14, is responsible for generating phosphatidylinositol 3-phosphate (PI3P) (Klionsky et al., 2021)