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Tirzepatide is sold as Zepbound for chronic weight management and as Mounjaro for type 2 diabetes, working as a dual GLP-1/GIP receptor agonist that targets both the GLP-1 and GIP receptors instead of GLP-1 alone, which enhances fat metabolism and insulin sensitivity beyond a single-receptor peptide

Metabolism 113 , 154388 (2020)

In terms of patient characteristics, the reduction in prostate cancer risk with GLP-1RAs is more significant in older male patients, and the expression of endogenous GLP-1 receptors has been linked to cancer risk

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These were often sold through med spas or online retailers