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The model was refined over multiple rounds of model building in Coot 77 and real-space refinement in Phenix 73

AOD-9604 targets fat cells directly, promoting their breakdown, while MOTS-C improves overall metabolic function and insulin sensitivity

Supplies Needed Plan based on an 816 week combined protocol with the schedules above

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Cell surface labeling plate reader trafficking GLP-1R internalization and recycling in CHO-SNAP-GLP-1R cells was measured by surface labeling with anti-GLP-1R antibody or the SNAP-tag probe Lumi4-Tb (Cisbio)