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Story so far: Mounjaros success has set a high bar

Curr Opin Nephrol Hypertens

Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with Type 2 diabetes (LEAD-1 SU)

Longer-term liraglutide administration at the highest dose approved for obesity increases reward-related orbitofrontal cortex activation in response to food cues: Implications for plateauing weight loss in response to anti-obesity therapies

Understanding the triple mechanism GLP-1 Activation Reduces appetite Increases satiety Slows gastric emptying Improves insulin secretion This pathway is responsible for the success of semaglutide-based therapies

To detect the release rate of GLP-1RAs@NPs-WYRGRL from MN/GLP-1RAs@NPs-WYRGRL, we first measured the absorbance of 2 ml of deionized water containing RBITC-GLP-1RAs@NPs-WYRGRL