The principles laid down by the OECD describe the organisational process and responsibilities as well as the conditions under which we plan, perform, monitor, record, report and archive the necessary laboratory tests for you
However, BMI isnt the only thing we consider
Duration of Benefit The health benefits of GLP-1R agonists are most pronounced within the first year of treatment, with significant improvements in glycated hemoglobin (HbA1c), body mass index (BMI), and cardiovascular outcomes
For a proof-of-concept related to efficacy, future studies would need to include primary endpoints that directly measure changes in body weight, body composition, or relevant metabolic markers such as blood glucose, insulin levels, or HbA1c for T2DM patients
Centonze et al., 2003), prefrontal cortex and hippocampus (cognition, learning, and memory) (Sawaguchi et al., 1990
The Phase 2 trial confirmed the robust efficacy and favorable safety profile seen in Phase 1