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Tesamorelin + ipamorelin work through complementary GH-release mechanisms: tesamorelin activates GHRH receptors on pituitary somatotrophs, while ipamorelin selectively stimulates ghrelin receptors without cortisol or prolactin elevation

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A different picture emerges from the glycemic trends in patients on psychotropic medications from our cohort studies: all patients on ADM in this and our previous study 22 had somewhat blunted HbA 1c reductions over a 12-month period

doi: 10.1038/nn1969 172 SalcedoI.TweedieD.LiY.GreigN