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For example, production of the neurotransmitter, 5-HT/serotonin, was reportedly upregulated in the presence of spore-forming Clostridia species , while germ-free mice displayed lower 5-HT/serotonin levels in their colon and blood as well as reduced intestinal motility (Kashyap et al

Weeks 8-12: Peak Effect Window Weeks 8 through 12 represent the peak efficacy window based on the Phase 2 trial duration

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Ito cells) are the principal effectors of liver fibrosis, transitioning from quiescent vitamin A-storing cells to activated myofibroblast-like cells (-SMA+

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Kumari, S., Panda, T