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Immunomodulation by vitamin B12: Augmentation of CD8+ T lymphocytes and natural killer (NK) cell activity in vitamin B12-deficient patients by methyl-B12 treatment

Apart from the enhanced activity of fibroblasts, which are pivotal in collagen synthesis, tissue repair, and regeneration, there was also noted a potential rise in mast cell activation

PMID 11298092

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The mRNA expression of IBAT and OST was significantly increased in NASH mice compared to control mice, and HZRG intervention significantly decreased their expression

So the inflammation is affecting the brain, right