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A 2008 follow-up in Inflammation Research characterized early functional recovery (days 14 post-transection) using the Achilles Functional Index, myeloperoxidase activity, and vascular index, and reported anti-inflammatory effects together with increased new vessel formation (Krivic et al., 2008)

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Injury healing protocols should plan reconstitution timing to match usage patterns, avoiding unnecessary degradation from extended reconstituted storage