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Mnnist, S., Kontto, J., Kataja-Tuomola, M., Albanes, D., & Virtamo, J

Broadly, studies suggest GLP-1RAs exert their neuroprotective effects in the retina by mediating reduced glutamate excitotoxicity, decreased neuroinflammation, prevention of retinal ganglion cell (RGC) loss, promotion of vascular integrity, promotion of an anti-oxidative environment, and maintenance of glial cells (i.e

The safety profile was consistent with GLP-1 receptor agonists, primarily featuring transient, mild-to-moderate gastrointestinal adverse events (e.g., nausea, 55%), with low discontinuation rates (6-8.4%)

Additionally, adipose (fat) tissue is a source of peripheral oestrogen synthesis via the conversion of androgens by the enzyme aromatase