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Low B12 levels contribute to increased levels of homocysteine, an amino acid that, in excess, can damage blood vessel walls and increase the risk of heart disease

Patients with a stressed myocardium should be observed carefully and the drug administered slowly since premature ventricular contractions may occur with rapid administration

The freeze-thaw cycle also concentrates solutes in unfrozen regions, creating localized conditions that accelerate chemical degradation

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Fraxel Repair is a CO2 device that also contains two wavelengths and can be used to achieve even better results in a shorter timeframe, albeit with greater downtime

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