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This can be interpreted as a surrogate for the compounds on-target activity (Fig

Cardiac Inflammation : High levels of pro-inflammatory markers such as C-reactive protein (CRP) are common in obese individuals and are linked to cardiovascular diseases

This variability likely reflects heterogeneity in the biological drivers of obesity across individuals, suggesting opportunity for precision medicine approaches that match patients to optimal therapeutic mechanisms

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Transcriptomic analyses of MSC-Ex-4 under glucose stimulation (25 mM) revealed 1323 differentially expressed genes, with enrichment patterns indicating regulatory effects on pathways related to proliferation, apoptosis, and cell cycle regulation