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For Study 6, the primary efficacy parameters were mean percent change in body weight and the percentage of patients achieving greater than or equal to 5% weight loss from baseline to Week 68

Daily totals up to 900 mcg (300 mcg three times per day) have been used in community protocols, but tolerability and side-effect risk climb at the high end

Frequency: Affects approximately 10% of those who experience diarrhea

Increasing evidence implicates oxidative stress (OS) with age-related neurodegeneration, neurotoxicity, and neuronal loss [12]

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Lichtstein D, Ilani A, Rosen H, Horesh N, Singh SV, Buzaglo N, et al