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One directly affects the somatotropic cells of the anterior pituitary, itself inhibiting further release of GH, whilst the other affects GH releasing hormone and somatostatin release from the hypothalamus to reduce the secretion of GH

Sermorelin, CJC-1295 and Ipamorelin instead stimulate the pituitary to release the bodys own growth hormone in a more natural pulsatile pattern

Due to the risk of severe drug interactions and other serious adverse effects with ketoconazole oral tablets, ketoconazole oral tablets should not be a first-line treatment for any fungal infection in the geriatric patient

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doi: 10.1148/radiol.2503080751 18 DanemanR.PratA

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