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It is also available as a generic drug, which means it can be produced by different manufacturers once the original patent expires

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Patients with acute kidney injury, severe dehydration, or recent contrast dye exposure should delay semaglutide initiation until kidney function stabilizes, as GLP-1 medications can theoretically worsen outcomes during acute renal stress

Dysbiosis, inflammation, and gut-derived metabolites are all critical factors in the progression of kidney disease

doi: 10.3748/wjg.v30.i5.485 228 SinhaSRHaileselassieYNguyenLPTropiniCWangMBeckerLSet al

Some of them have to be refrigerated