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Subsequently, AA undergoes enzymatic conversion through two principal pathways: the cyclooxygenase (COX) pathway, which generates prostaglandins (PGs), and the lipoxygenase (LOX) pathway, which produces leukotrienes (LTs), lipoxins (LXs), and hydroxyeicosatetraenoic acids (HETEs) [160]

This study has highlighted that reporting gaps exist for clinical trials supported by public funding as well as for trials that have been approved

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Baseline labs should include serum copper, ceruloplasmin, 24-hour urine copper, and a comprehensive metabolic panel

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Manchha AV, Walker N, Way KA, Dawson D, Tann K, Thai M