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Full effects may vary depending on your B12 levels and overall health

The link starts with appetite and thirst signaling

The data tells a different story: | Side Effect | Semaglutide | Retatrutide | |-------------|-------------|-------------| | Nausea | 40-45% | 24-35% | | Diarrhea | 25-30% | 15-25% | | Vomiting | 20-25% | 10-15% | | Constipation | 20-25% | 10-20% | | Heart rate increase | Not significant | 5-10 bpm | Retatrutide's nausea rates are actually lower than semaglutide's in their respective trials

The milligrams refer to different molecular weights, different receptor affinities, and different potency profiles

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doi: 10.1210/jc.2002-021479 101 ZanderMMadsbadSDeaconCFHolstJJ