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Inflammatory activation serves a notable role in this process, as M1 macrophage infiltration and the release of pro-inflammatory cytokines, such as TNF-, IL-1 and IL-6, accelerate ECM degradation and promote cell death (38)

BMI was divided into three groups based on the criterion from World Health Organization [28], including normal or low body weight ( 30 kg/m 2 )

doi: 10.3390/ijms232113470 229 ElyadaEBolisettyMLaisePFlynnWFCourtoisETBurkhartRAet al

Changes in hormone levels may affect how the brain processes information

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2018;20(6):e216