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According to a study in Neurology International published in August 2014, different vitamin deficiencies, including vitamin B12 deficiency, can cause muscle twitching

Biol Chem 390:191214 Kulaksiz-Erkmen G, Dalmizrak O, Dincsoy-Tuna G, Dogan A, Ogus IH, Ozer N (2013) Amitriptylin may have a supporting role in cancer treatment by inhibiting glutathione S-transferase pi (GST-) and alpha (GST-)

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Oxidative stress and environmental toxins do most of the heavy lifting in that process, quietly degrading cells long before the visible signs show up

doi: 10.1016/j.cell.2013.12.010 14 ShenQLiangMYangFDengYZNaqviNI

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