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This structural modification disrupts the Keap1-cullin-3 ubiquitin ligase complex liberating Nrf2 and allowing its stabilization and migration into the nucleus [65]
Real-time PCR was performed on ABI Stratagene Mx3000P instrument (Agilent Technologies, Santa Clara, CA, USA) using a TB Green Premix Ex Taq II (Takara Biomedical Technology, Beijing)
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Some researchers combine cerebrolysin with Semax (for acute cognitive enhancement) and Selank (for anxiolytic effects)
c The statistical analysis did not show differences in GSH ( H 3 = 6.02, p = 0.11) or GSHc ( H 3 = 5.98, p = 0.11) levels among groups (Figures 3A,B)