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These compounds are highly lipophilic, and for this reason, accumulate preferentially in the adipose tissue [240]

The Se content of food is strongly dependent on the Se content of the soil in which plants and animals grow (104106)

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Given the physiological changes that occur during this period due to puberty, the strong sex differences in migraine epidemiology and symptomatology in adults 56 , and that migraine prevalence sharply increases in females following puberty 57 , a key question that follows from this study is the effects of sex and puberty on these neurometabolite changes

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