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The Pharmacy Compounding Advisory Committee voted 8 in favor, 6 against, with 1 abstention

Neelakantan H, Wang HY, Vance V, Hommel JD, McHardy SF, Watowich SJ

Advantage: Potential for higher bioavailability than standard oral ingestion Challenge: Peptides are poorly absorbed through intact mucosal membranes without transport mechanisms Evidence: No studies confirm enhanced sublingual bioavailability for Dihexa Standard oral (swallowed): Tablets swallowed with water, absorbed through the gastrointestinal tract

Researchers became interested in this compound because of its connection to cellular movement, tissue structure organization and adaptation

Notably, the panel currently has several vacancies, which Kennedy could fill with new appointments before the July meeting, a detail that has drawn concern from regulatory oversight advocates

Vitamin B-12 supplementation during pregnancy and early lactation increases maternal, breast milk, and infant measures of vitamin B-12 status