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Specifically, it acts as an agonist (activator) for the glucagon-like peptide-1 (GLP-1) receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor

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SES Numerically, Not Statistically, Superior to ZES at 5-Years in SUGAR Study Mar 07, 2026 by Natalie Morrison, CRTonline.org A sirolimus-eluting stent (SES) saw a numerical improvement in target lesion failure (TLF) rates for diabetes mellitus (DM) at 5-year follow-up compared to a zotarolimus-eluting stent (ZES) but did not maintain the 1-year statistical significance, the latest report from the SUGAR study shows

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