difference between gip and glp-1 How May Enhance the Therapeutic Efficacy of GLP-1? Frontiers | Mechanisms of action

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Co-localization with RNA-polymerase II and binding to chromatin, as shown by co-precipitation with histone H3, further support a transcriptional regulation role for IGF-1R [88,89]

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This distinction matters enormously and it is often completely ignored in how GLP-1 therapy is monitored