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This can lead to loose and uncoordinated movement of the intestines, which slows digestion

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Aim for a modest caloric deficit of 300-500 calories below maintenance, with protein intake around 0.8-1 gram per pound of body weight

Obese patients often have gut microbiota dysbiosis, with BA metabolism disrupted, as evidenced by abnormal portal vein bile acids (BAs) (Sayin et al., 2013

[1] [2] All processes of cellular respiration, including glycolysis in the cytoplasm, the Krebs cycle, and the electron transport chain in the mitochondria, depend on NAD+ and its redox partner NADH to produce energy (ATP)

IL-6, interleukin-6