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[7] Hydroxocobalamin is the preferred formulation in the UK and carries a lower risk profile, though it may cause a harmless reddish discolouration of urine

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The dominant adverse events in both are gastrointestinal nausea, diarrhea, vomiting, and constipation and in both they are dose-dependent and tend to ease as the body adapts to gradual dose escalation

Sugar-free gum or lozenges can stimulate saliva production and provide temporary relief, while mouth rinses specifically formulated for xerostomia can coat oral tissues and reduce discomfort