The once-daily modified-release version did not meet development targets and was halted in June 2024
Reference Snchez-Feliciano A et al
After achieving target weight, it may be useful to taper the drug to the lowest possible dose while sharply refocusing on diet and exercise. Dr Mohan added that in countries where GLP-1 drugs have been used for many years, patients and clinicians have experimented with intermediate strategies to blunt rebound effects
Eat slowly, pausing between bites, and stop at comfortable fullness
Termed sarcopenic obesity, it is characterised by the concurrent decline in muscle mass and function along with increased levels of adipose tissue and is associated with higher risk of disability, metabolic dysfunction, comorbidities, e.g., T2D, chronic kidney disease, cardiovascular disease, and all-cause mortality [2, 3]
Incorporating semaglutide into a comprehensive approach to body contouring and weight management offers patients the opportunity to maximize their aesthetic goals