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Most populations were conserved across species, with macaques expressing Calcr and Ramp3 in similar cell populations as rodents

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But they work through entirely separate receptor systems, activating different neural pathways and producing complementary effects when combined

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Instead, HC induced a reduction of red fluorescence compared to the DMSO condition similar to CCCP, a known mitochondrial membrane disruptor which causes a complete mitochondria depolarization (Figure 7A)