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doi: 10.1136/jmedgenet-2021-107965 51 ChiA.LogroscinoG.TraynorB

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The gastrointestinal side effects compound this problem

Metformin studies demonstrate significant improvements in menstrual regularity, lower androgen levels, and weight reduction in women with PCOS

17 Detection of elevated levels of these APAP-protein adducts by high-pressure liquid chromatography (HPLC) can be used for clinical indication of APAP hepatotoxicity