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Protein structure visualization graphics were generated with UCSF ChimeraX, 604 developed by the Resource for Biocomputing, Visualization, and Informatics at the University of California, San Francisco, with support from National Institutes of Health R01GM129325 and the Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases

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Semaglutide presents unique analytical challenges because of its lipid conjugation and heterogeneity, while exenatide requires sensitive monitoring for oxidation, deamidation, and truncation impurities

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