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As such, p53 has been described as "the guardian of the genome" because of its role in conserving stability by preventing genome mutation

Under normal physiological conditions the NO increase might be controlled by S-nitrosylation/glutathionylation of eNOS as an immediate response or by similar modification/activation of SERCA in steady-state regulation

pkCSM: predicting small-molecule pharmacokinetic and toxicity properties using graph-based signatures

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These are considered one of the more bioavailable options because glutathione can be difficult to absorb in its standard form