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This is most dramatically illustrated through differences in the intake patterns of the same drug with different routes of administration 45,46,47,48,49,50,58 known as the rate hypothesis of addiction 49,59,60

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Bruce-Keller AJ, Salbaum JM, Luo M, Blanchard E, Taylor CM, Welsh DA, et al

Better sleep, in turn, supports healthy hormone production, creating a positive feedback loop