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Conclusion and Future Directions A minor change in the complex brain can lead to enormous changes in the neuronal network

Studies have demonstrated that individuals with ASD may have abnormal production of melatonin, and preliminary studies have shown melatonin to be a safe and effective sleep aid in children with ASD

Secondly, IGF-2R is crucial for transporting lysosomal enzymes from the trans-Golgi network to endosomes [227]

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