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As inflammation rises, the enzymes responsible for breaking down histamines become less effective, making it increasingly difficult for your body to regulate its immune response and restore balance

Managing Side Effects Proactively The most common early side effects nausea, constipation, and fatigue are manageable with the right habits and largely resolve after the first few dose escalations

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doi:10.1056/NEJMoa160714 Reserved Perkovic V, Tuttle KR, Rossing P, et al

Persistent Symptoms Deserve Review Constipation, fatigue or very low appetite should not simply be ignored because they are considered common

and influencing gene expression across thousands of human genes