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They are pathway-level and do not predict response to a specific compound

10.1111/j.1600-0838.2011.01377.x 78 KvorningT.AndersenM.BrixenK.SchjerlingP.SuettaC.MadsenK

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"Pleiotropic effects of GIP receptor stimulation in other tissues, mediated by mechanisms other than typical protein G-coupled receptor pathways, might bring additional benefits